Yazar "Bora, Ejder Saylav" için listeleme
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Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexate-induced hepatoxicity model
Acar, Huseyin; Sorgun, Omay; Yurtseve, Guner; Bora, Ejder Saylav; Erbas, Oytun (Acta Cirurgica Brasileira, 2022)Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of ... -
Autophagy and anti-inflammation ameliorate diabetic neuropathy with Rilmenidine
Yalcin, Mehmet Burak; Bora, Ejder Saylav; Cakir, Adem; Akbulut, Sabiye; Erbas, Oytun (Acta Cirurgica Brasileira, 2023)Purpose: To evaluate the neuroprotective effects of Rilmenidine on diabetic peripheral neuropathy (DPN) in a rat model of diabetes induced by streptozotocin (STZ). Methods: STZ (60 mg/kg) was administered to adult ... -
The Effect of Adipose-Derived Mesenchymal Stem Cells on Peripheral Nerve Damage in a Rodent Model
Yalcin, Mehmet Burak; Bora, Ejder Saylav; Erdogan, Muemin Alper; Cakir, Adem; Erbas, Oytun (Mdpi, 2023)Peripheral nerve damage is a significant clinical problem with limited therapeutic options. Adipose-derived mesenchymal stem cells (ADSCs) have emerged as a promising therapeutic approach due to their regenerative potential. ... -
Effect of celecoxib on intra-abdominal sepsis-induced lung injury in rats
Dibekoğlu, Cengiz; Bora, Ejder Saylav; Eroğlu, Ebru; Yurtsever, Guner; Uyanikgil, Yiğit; Erbaş, Oytun (2023)Objectives: This experimental study investigated the preventive effects of Celecoxib, a selective COX-2 inhibitor, on lung injury induced by intra-abdominal sepsis in rats. The study assessed Celecoxib's potential to ... -
Protective effect of dapagliflozin on colistin-induced renal toxicity
Bora, Ejder Saylav; Erdogan, Mumin Alper; Meral, Ayfer; Karakaya, Zeynep; Erbas, Oytun (Mre Press, 2021)Objectives: Multiple-drug resistance to Gram-negative bacteria has increased significantly in recent years. Colistin is increasingly used as a last line of defense against these bacteria. However, colistin has been associated ... -
Research Article Nasal Oxytocin's Anticonvulsant Effects on Pentylenetetrazolinduced Convulsions in Rats
Bora, Ejder Saylav; Erdogan, Mumin Alper; Karaali, Rezan; Cakir, Adem; Erbas, Oytun (Asian Network Scientific Information-Ansinet, 2023)Background and Objective: Neurodegenerative proteins and pro-inflammatory mechanisms may cause epilepsy through excitatory-inhibitory imbalance. Drug resistance is common, therefore this disease requires affordable, ... -
Short term protective effect of digitoxin in sepsis-induced acute lung injury
Bora, Ejder Saylav; Erdogan, MuMIN Alper; Ozkul, Bahattin; Sever, Ibrahim Halil; Sogut, Ibrahim; Hurdag, Canan; Erbas, Oytun (Tech Science Press, 2022)Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light ... -
Short term protective effect of digitoxin in sepsis-induced acute lung injury
Bora, Ejder Saylav; Erdogan, MuMIN Alper; Ozkul, Bahattin; Sever, Ibrahim Halil; Sogut, Ibrahim; Hurdag, Canan; Erbas, Oytun (Tech Science Press, 2022)Purpose: Digitoxin is a cardiac glycoside used in the treatment of heart failure. Inspired by its known antiinflammatory effect, this study aims to investigate the effect of digoxin in a sepsis model and to bring to light ...